Portfolio Companies

Achillion Pharmaceuticals
Next generation antivirals
Endoscopy systems. Acquired by Gyrus Corporation, now Olympus.
ActivX Biosciences *
Molecularly targeted therapeutics. Acquired by Kyorin.
Acurian *
Clinical trials recruitment
Aerovance *
Novel therapeutics for the manegement of asthma
Affymax *
Supportive care for life-threatening conditions
Agile Therapeutics
Women's health pharmaceuticals
Artemis Medical *
Minimally-invasive tumor biopsy. Acquired by Johnson & Johnson.
Avanir Pharmaceuticals *
Novel CNS drugs
Axys Pharmaceuticals *
Technology-driven drug discovery
BioRexis *
Protein engineering for improved biologics. Acquired by Pfizer.
Biosyntech *
Advanced biotherapeutic thermogels
Cabrellis Pharmaceuticals *
Small molecule cancer therapeutics. Acquired by Pharmion, now Celgene Corp.
Cadence Pharmaceuticals *
Hospital specialty pharmaceuticals
Cell Therapeutics *
Cancer therapeutics
Cervelo Pharmaceuticals*
Pain therapeutics
Clarus Therapeutics
Next generation testosterone therapy
Clovis Oncology*
Specialty cancer pharmaceuticals
Concentric Medical *
Minimally invasive devices. Acquired by Stryker Corporation.
Conforma Therapeutics *
Small molecule cancer. Acquired by Biogen Idec. Therapeutics
Cypress Bioscience *
Pain and CNS therapeutics
Cytogen *
Specialty products for oncology and pain
Eagle Pharmaceutical
Specialty pharmaceuticals
Eos Biotechnology *
Therapeutic antibodies. Acquired by PDL Biopharma.
Epic Therapeutics *
Microsphere-based drug delivery. Acquired by Baxter.
Excaliard Pharmaceuticals*
Novel skin therapeutics. Acquired by Pfizer.
Gemin X Biotechnologies *
Small molecule cancer therapeutics. Acquired by Cephalon, now Teva.
Genta *
Cancer therapeutics
Gloucester Pharmaceuticals *
Cancer therapeutics. Acquired by Celgene Corp.
Guava Technologies *
Cell analysis platform. Acquired by Millipore.
Immune Design Corporation
Develops next generation adjuvants
Iomai Corporation *
Transcutaneous immunization. Acquired by Intercell.
Keryx Biopharmaceuticals *
Cancer and renal therapeutics
LEAD Therapeutics *
Novel oncology therapeutics and anti-infectives. Acquired by BioMarin
Mast Therapeutics
Pulmonary-focused drug development
Mersana Therapeutics
Novel polymer-based therapeutics
MethylGene *
Small molecule enzyme inhibitors
NovaDel Pharma
Novel delivery of pharmaceuticals
Oncology.com *
Cancer information website
Optimer Pharmaceuticals *
Anti-infective therapeutics
Orthocon *
Orthopedics medical devices
Palatin Technologies *
Novel receptor-mediated therapeutics
Palkion *
Novel therapeutics to treat anemia
First in class cancer therapy
Pharmion *
Specialty cancer pharmaceuticals. Acquired by Celegene Corp.
Point Therapeutics *
Small molecule cancer therapeutics
Predictive *
Anatomic pathology laboratory & proprietary diagnostic development
Implantable medical devices to improve vision
Rigel Pharmaceuticals *
Anti-inflammatory therapeutics
Salmedix *
Specialty oncology products. Acquired by Cephalon, now Teva.
Aptamer-based microarrays
Sopherion Therapeutics
Cancer therapeutics
Cancer therapeutics
Threshold Pharmaceuticals *
Metabolic targeting in oncology
Tragara Pharmaceuticals
Cancer and anti-inflammatory therapeutics
Transcept *
CNS-focused specialty pharma
US Bioscience *
Cancer therapeutics. Acquired by Medimmune.
Ziopharm Oncology *
Small molecule cancer therapeutics
Zosano Pharma
Novel microneedle transdermal patch technology
* Exited Investments